The secretogogue hexipeptide Hexarelin, also known as Hex, is a peptide whose structure is comprised of a chain of six amino acids. Its structure is similar to GHRP 6, which is another secretogogue peptide. It has a molecular weight of 1024.2, and its molecular structure is C50H69N15O9.
Hexarelin’s Relationship with the Brain
According to scientific study that has been conducted on animal test subjects, it has been determined that Hexarelin has a functional relationship with two components of the brain.
Those components are:
- The pituitary gland – This pea-sized gland is located at the bottom of the hypothalamus at the base of the brain. In essence, it functions as the command center for the endocrine system, as it is responsible for the regulation and control of several endocrine system-related functions, including growth, metabolism, pain relief, and more.
- The hypothalamus – This section of the brain serves as the connecting point between the endocrine system and the central nervous system, as both vital systems are linked together here via the pituitary gland.
Although it is known that Hexarelin functions in conjunction with these two brain components, it is unsure as to how exactly the peptide operates in order to create this functional relationship.
The Difference between Hexarelin and Other Secretogogue Peptides
Despite the fact that scientific study based on animal test subjects has yet to pinpoint exactly how Hexarelin operates, there have been enough results derived from observing results from its functionality to allow studies to compare and contrast it with other peptides that are classified as secretogogues, such as GHRP-6. For instance, it has been determined that like other secretogogues in its class, it has the ability to boost the production of IGF-1, also known as Insulin-like Growth Factor-1 or Somatomedin C.
Produced by the liver in animal test subjects, the expression of this secretion has been determined to be highly reactive, meaning that it plays a key role in the growth and repair of muscular and skeletal tissues. Because it can influence an uptick in the production of this secretion, it is determined that the peptide can be conceivably tied to a boost in several bodily functions that are tied to muscular and skeletal tissues, including an elevated rate of muscle development and an increased measure of bone density. It has also been determined that unlike other secretogogues like GHRP-6, Hexarelin’s functionality does not increase ghrelin production.
Ghrelin is the 28 amino acid enzyme that is produced by the stomach of animal test subjects as a means to stimulate the sensation of hunger. Because Hexarelin does not promote a boost in the production of this enzyme, it has been determined that its presence still allows animal test subjects to enjoy a measure of homeostasis when it comes to food intake.
Hexarelin’s Relationship with the Heart
One of the key focuses of scientific study based on animal test subjects related to Hexarelin involves researching the correlation that seemingly exists between it and the heart. This research has suggested that it could contain properties that may cause protective cardio-based effect. This particular field of research was conducted by comparing lab rats with growth hormone deficiencies to lab rats that did not. As part of this study, several of the lab rats underwent a process in which their pituitary glands were removed. These rats were then administered Hexarelin for a week via subcutaneous injection. Over the duration of the study, the injections were deemed to inhibit an increased measure of left ventricular or diastolic pressure within the heart.
Furthermore, it was determined to lessen the reactivity of the coronary vasculature to angiotensin II and coronary perfusion pressure. Additionally, it was noted that it could halt the release of prostacyclin while the heart contracted. Essentially, the results of the data that was derived strongly indicated that Hexarelin could contain the ability to lower the damage that could occur to the cardiovascular system during an episode that is brought about by a growth hormone deficiency. While these results have been the product of research, it has led to the theory that Hexarelin could play a key role in the preventative care for growth-hormone issues related to cardiovascular based concerns, up to and including serious episodes such as the recovery stage in the wake of a heart attack.
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